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Itaconic acid mediates crosstalk between macrophage metabolism and peritoneal tumors
Control of cellular metabolism is critical for efficient cell function, although little is known about the interplay between cell subset–specific metabolites in situ, especially in the tumor setting. Here, we determined how a macrophage-specific (Mϕ-specific) metabolite, itaconic acid, can regulate...
Autores principales: | Weiss, Jonathan M., Davies, Luke C., Karwan, Megan, Ileva, Lilia, Ozaki, Michelle K., Cheng, Robert Y.S., Ridnour, Lisa A., Annunziata, Christina M., Wink, David A., McVicar, Daniel W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6118601/ https://www.ncbi.nlm.nih.gov/pubmed/29920191 http://dx.doi.org/10.1172/JCI99169 |
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