Cargando…

Dynamic interplay between enhancer-promoter topology and gene activity

A long-standing question in gene regulation is how remote enhancers communicate with their target promoters, and specifically how chromatin topology dynamically relates to gene activation. Here, we combine genome editing and multi-color live imaging to simultaneously visualize physical enhancer–prom...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Hongtao, Levo, Michal, Barinov, Lev, Fujioka, Miki, Jaynes, James B., Gregor, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119122/
https://www.ncbi.nlm.nih.gov/pubmed/30038397
http://dx.doi.org/10.1038/s41588-018-0175-z