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Dynamic interplay between enhancer-promoter topology and gene activity
A long-standing question in gene regulation is how remote enhancers communicate with their target promoters, and specifically how chromatin topology dynamically relates to gene activation. Here, we combine genome editing and multi-color live imaging to simultaneously visualize physical enhancer–prom...
Autores principales: | Chen, Hongtao, Levo, Michal, Barinov, Lev, Fujioka, Miki, Jaynes, James B., Gregor, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119122/ https://www.ncbi.nlm.nih.gov/pubmed/30038397 http://dx.doi.org/10.1038/s41588-018-0175-z |
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