Pharmacological inhibition of dihydroorotate dehydrogenase induces apoptosis and differentiation in acute myeloid leukemia cells

Acute myeloid leukemia is a disorder characterized by abnormal differentiation of myeloid cells and a clonal proliferation derived from primitive hematopoietic stem cells. Interventions that overcome myeloid differentiation have been shown to be a promising therapeutic strategy for acute myeloid leu...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Dang, Wang, Wanyan, Chen, Wuyan, Lian, Fulin, Lang, Li, Huang, Ying, Xu, Yechun, Zhang, Naixia, Chen, Yinbin, Liu, Mingyao, Nussinov, Ruth, Cheng, Feixiong, Lu, Weiqiang, Huang, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119157/
https://www.ncbi.nlm.nih.gov/pubmed/29880605
http://dx.doi.org/10.3324/haematol.2018.188185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119157/
https://www.ncbi.nlm.nih.gov/pubmed/29880605
http://dx.doi.org/10.3324/haematol.2018.188185

Ejemplares similares