Transient inhibition of NF-κB signaling enhances ex vivo propagation of human hematopoietic stem cells

Despite extensive studies, defining culture conditions in which hematopoietic stem cells can be expanded ex vivo has been challenging. Here we show that chemical inhibition of the NF-κB signaling pathway leads to a significant improvement of hematopoietic stem cell function from ex vivo cultured hum...

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Detalles Bibliográficos
Autores principales: Talkhoncheh, Mehrnaz Safaee, Subramaniam, Agatheeswaran, Magnusson, Mattias, Kumar, Praveen, Larsson, Jonas, Baudet, Aurélie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119158/
https://www.ncbi.nlm.nih.gov/pubmed/29880606
http://dx.doi.org/10.3324/haematol.2018.188466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119158/
https://www.ncbi.nlm.nih.gov/pubmed/29880606
http://dx.doi.org/10.3324/haematol.2018.188466

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