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Transient inhibition of NF-κB signaling enhances ex vivo propagation of human hematopoietic stem cells
Despite extensive studies, defining culture conditions in which hematopoietic stem cells can be expanded ex vivo has been challenging. Here we show that chemical inhibition of the NF-κB signaling pathway leads to a significant improvement of hematopoietic stem cell function from ex vivo cultured hum...
Autores principales: | Talkhoncheh, Mehrnaz Safaee, Subramaniam, Agatheeswaran, Magnusson, Mattias, Kumar, Praveen, Larsson, Jonas, Baudet, Aurélie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119158/ https://www.ncbi.nlm.nih.gov/pubmed/29880606 http://dx.doi.org/10.3324/haematol.2018.188466 |
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