Anti-TLR2 antibody triggers oxidative phosphorylation in microglia and increases phagocytosis of β-amyloid

BACKGROUND: Microglia are multifunctional cells that are primarily neuroprotective and a deficit in their functional integrity is likely to be a contributory factor in the deteriorating neuronal function that occurs with age and neurodegeneration. One aspect of microglial dysfunction is reduced phag...

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Detalles Bibliográficos
Autores principales: Rubio-Araiz, Ana, Finucane, Orla M., Keogh, Samuel, Lynch, Marina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119264/
https://www.ncbi.nlm.nih.gov/pubmed/30170611
http://dx.doi.org/10.1186/s12974-018-1281-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119264/
https://www.ncbi.nlm.nih.gov/pubmed/30170611
http://dx.doi.org/10.1186/s12974-018-1281-7

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