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A new adult AML case with an extremely complex karyotype, remission and relapse combined with high hyperdiploidy of a normal chromosome set in secondary AML

BACKGROUND: Chromosomal abnormalities are diagnostic and prognostic key factors in acute myeloid leukemia (AML) patients, as they play a central role for risk stratification algorithms. High hyperdiploidy (HH), a rare cytogenetic abnormality seen commonly in elder male AML patients, is normally cate...

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Detalles Bibliográficos
Autores principales: Wafa, Abdulsamad, ALmedania, Suher, Aljapawe, Abdulmunim, Liehr, Thomas, Soulaiman, Soulaiman E., Mouna, Raja, Othman, Moneeb A. K., ALachkar, Walid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119272/
https://www.ncbi.nlm.nih.gov/pubmed/30186609
http://dx.doi.org/10.1186/s12878-018-0114-3