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Novel recombinant feline interferon carrying N-glycans with reduced allergy risk produced by a transgenic silkworm system

BACKGROUND: The generation of recombinant proteins for commercialisation must be cost-effective. Despite the cost-effective production of recombinant feline interferon (rFeIFN) by a baculovirus expression system, this rFeIFN carries insect-type N-glycans, with core α 1,3 fucosyl residues that act as...

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Detalles Bibliográficos
Autores principales: Minagawa, Sachi, Nakaso, Yuzuru, Tomita, Masahiro, Igarashi, Takenori, Miura, Yoshio, Yasuda, Hideyo, Sekiguchi, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119277/
https://www.ncbi.nlm.nih.gov/pubmed/30170576
http://dx.doi.org/10.1186/s12917-018-1584-z