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Effect of tryptase on mouse brain microvascular endothelial cells via protease-activated receptor 2
BACKGROUND: Mast cells (MCs), the ‘first responders’ in brain injury, are able to disrupt the blood–brain barrier (BBB), but the underlying mechanism is not well understood. Tryptase is the most abundant MC secretory product. Protease-activated receptor 2 (PAR-2) has been identified as a specific re...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119285/ https://www.ncbi.nlm.nih.gov/pubmed/30170602 http://dx.doi.org/10.1186/s12974-018-1287-1 |