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Effect of tryptase on mouse brain microvascular endothelial cells via protease-activated receptor 2

BACKGROUND: Mast cells (MCs), the ‘first responders’ in brain injury, are able to disrupt the blood–brain barrier (BBB), but the underlying mechanism is not well understood. Tryptase is the most abundant MC secretory product. Protease-activated receptor 2 (PAR-2) has been identified as a specific re...

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Detalles Bibliográficos
Autores principales:	Zhou, Qin, Wang, Yi-wei, Ni, Peng-fei, Chen, Yi-nan, Dong, Hong-quan, Qian, Yan-ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119285/ https://www.ncbi.nlm.nih.gov/pubmed/30170602 http://dx.doi.org/10.1186/s12974-018-1287-1

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