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Structurally Related Kappa Opioid Receptor Agonists with Substantial Differential Signaling Bias: Neuroendocrine and Behavioral Effects in C57BL6 Mice

BACKGROUND: The kappa opioid receptor system has been revealed as a potential pharmacotherapeutic target for the treatment of addictions to substances of abuse. Kappa opioid receptor agonists have been shown to block the rewarding and dopamine-releasing effects of psychostimulants. Recent investigat...

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Detalles Bibliográficos
Autores principales: Dunn, Amelia D, Reed, Brian, Guariglia, Catherine, Dunn, Alexandra M, Hillman, Joshua M, Kreek, Mary Jeanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119295/
https://www.ncbi.nlm.nih.gov/pubmed/29635340
http://dx.doi.org/10.1093/ijnp/pyy034