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Structurally Related Kappa Opioid Receptor Agonists with Substantial Differential Signaling Bias: Neuroendocrine and Behavioral Effects in C57BL6 Mice
BACKGROUND: The kappa opioid receptor system has been revealed as a potential pharmacotherapeutic target for the treatment of addictions to substances of abuse. Kappa opioid receptor agonists have been shown to block the rewarding and dopamine-releasing effects of psychostimulants. Recent investigat...
Autores principales: | Dunn, Amelia D, Reed, Brian, Guariglia, Catherine, Dunn, Alexandra M, Hillman, Joshua M, Kreek, Mary Jeanne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119295/ https://www.ncbi.nlm.nih.gov/pubmed/29635340 http://dx.doi.org/10.1093/ijnp/pyy034 |
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