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Unleashing endogenous TNF-alpha as a cancer immunotherapeutic

Tumor necrosis factor (TNF)-alpha was originally identified in the 1970s as the serum mediator of innate immunity capable of inducing hemorrhagic necrosis in tumors. Today, a wide spectrum of biological activities have been attributed to this molecule, and clinical translation has mainly occurred no...

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Detalles Bibliográficos
Autores principales: Josephs, Steven F., Ichim, Thomas E., Prince, Stephen M., Kesari, Santosh, Marincola, Francesco M., Escobedo, Anton Rolando, Jafri, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119315/
https://www.ncbi.nlm.nih.gov/pubmed/30170620
http://dx.doi.org/10.1186/s12967-018-1611-7