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Unleashing endogenous TNF-alpha as a cancer immunotherapeutic
Tumor necrosis factor (TNF)-alpha was originally identified in the 1970s as the serum mediator of innate immunity capable of inducing hemorrhagic necrosis in tumors. Today, a wide spectrum of biological activities have been attributed to this molecule, and clinical translation has mainly occurred no...
Autores principales: | Josephs, Steven F., Ichim, Thomas E., Prince, Stephen M., Kesari, Santosh, Marincola, Francesco M., Escobedo, Anton Rolando, Jafri, Amir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119315/ https://www.ncbi.nlm.nih.gov/pubmed/30170620 http://dx.doi.org/10.1186/s12967-018-1611-7 |
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