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Screening for potential prophylactics targeting sporozoite motility through the skin

BACKGROUND: Anti-malarial compounds have not yet been identified that target the first obligatory step of infection in humans: the migration of Plasmodium sporozoites in the host dermis. This movement is essential to find and invade a blood vessel in order to be passively transported to the liver. H...

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Detalles Bibliográficos
Autores principales: Douglas, Ross G., Reinig, Miriam, Neale, Matthew, Frischknecht, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119338/
https://www.ncbi.nlm.nih.gov/pubmed/30170589
http://dx.doi.org/10.1186/s12936-018-2469-0