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Screening for potential prophylactics targeting sporozoite motility through the skin
BACKGROUND: Anti-malarial compounds have not yet been identified that target the first obligatory step of infection in humans: the migration of Plasmodium sporozoites in the host dermis. This movement is essential to find and invade a blood vessel in order to be passively transported to the liver. H...
Autores principales: | Douglas, Ross G., Reinig, Miriam, Neale, Matthew, Frischknecht, Friedrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119338/ https://www.ncbi.nlm.nih.gov/pubmed/30170589 http://dx.doi.org/10.1186/s12936-018-2469-0 |
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