Treatment of Trypanosoma cruzi with 2-bromopalmitate alters morphology, endocytosis, differentiation and infectivity

BACKGROUND: The palmitate analogue 2-bromopalmitate (2-BP) is a non-selective membrane tethered cysteine alkylator of many membrane-associated enzymes that in the last years emerged as a general inhibitor of protein S-palmitoylation. Palmitoylation is a post-translational protein modification that a...

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Detalles Bibliográficos
Autores principales: Batista, Cassiano Martin, Kessler, Rafael Luis, Eger, Iriane, Soares, Maurilio José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119340/
https://www.ncbi.nlm.nih.gov/pubmed/30170543
http://dx.doi.org/10.1186/s12860-018-0170-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119340/
https://www.ncbi.nlm.nih.gov/pubmed/30170543
http://dx.doi.org/10.1186/s12860-018-0170-3

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