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Defining the short-term effects of pharmacological 5′-AMP activated kinase modulators on mitochondrial polarization, morphology and heterogeneity

BACKGROUND: Under aerobic growth conditions, mitochondria are the major producers of cellular ATP and crucial for the proper performance of organs and tissues. This applies especially to cells with high energy demand, such as the renal proximal tubule epithelium. Mitochondrial dysfunction contribute...

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Detalles Bibliográficos
Autores principales: Kodiha, Mohamed, Flamant, Etienne, Wang, Yi Meng, Stochaj, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119600/
https://www.ncbi.nlm.nih.gov/pubmed/30186684
http://dx.doi.org/10.7717/peerj.5469