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Correlation between progression‐free survival, tumor burden, and circulating tumor DNA in the initial diagnosis of advanced‐stage EGFR‐mutated non‐small cell lung cancer

BACKGROUND: This study was conducted to identify whether the presence of circulating tumor DNA (ctDNA) in plasma before treatment with EGFR‐tyrosine kinase inhibitors (TKIs) is associated with clinical outcomes. METHODS: Fifty‐seven pairs of tissues and plasma samples were obtained from patients wit...

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Detalles Bibliográficos
Autores principales: Lee, Yunkyoung, Park, Sojung, Kim, Woo Sung, Lee, Jae Cheol, Jang, Se Jin, Choi, Jene, Choi, Chang‐Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119619/
https://www.ncbi.nlm.nih.gov/pubmed/29989342
http://dx.doi.org/10.1111/1759-7714.12793