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Role of Ezrin Phosphorylation in HIV-1 Replication

Host-cell expression of the ezrin protein is required for CXCR4 (X4)-tropic HIV-1 infection. Ezrin function is regulated by phosphorylation at threonine-567. This study investigates the role of ezrin phosphorylation in HIV-1 infection and virion release. We analyzed the effects of ezrin mutations in...

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Detalles Bibliográficos
Autores principales: Kamiyama, Haruka, Izumida, Mai, Umemura, Yuria, Hayashi, Hideki, Matsuyama, Toshifumi, Kubo, Yoshinao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119696/
https://www.ncbi.nlm.nih.gov/pubmed/30210460
http://dx.doi.org/10.3389/fmicb.2018.01912