Action potential clamp characterization of the S631A hERG mutation associated with short QT syndrome

The hERG potassium channel is critical to normal repolarization of cardiac action potentials (APs) and loss‐ and gain‐of‐function hERG mutations are associated, respectively, with long and short QT syndromes, pathological conditions that can lead to arrhythmias and sudden death. hERG current (I (h)...

Descripción completa

Detalles Bibliográficos
Autores principales: Butler, Andrew, Zhang, Yihong, Stuart, Alan G., Dempsey, Christopher E., Hancox, Jules C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119704/
https://www.ncbi.nlm.nih.gov/pubmed/30175559
http://dx.doi.org/10.14814/phy2.13845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119704/
https://www.ncbi.nlm.nih.gov/pubmed/30175559
http://dx.doi.org/10.14814/phy2.13845

Ejemplares similares