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Optogenetic Stimulation of GABAergic Neurons in the Globus Pallidus Produces Hyperkinesia

The globus pallidus (GP) is emerging as a critical locus of basal ganglia control of motor activity, but the exact role of GABAergic GP neurons remain to be defined. By targeted expression of channelrhodopsin 2 (ChR2) in GABAergic neurons using the VGAT-ChR2-EYFP transgenic mice, we showed that opto...

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Detalles Bibliográficos
Autores principales: Tian, Jun, Yan, Yaping, Xi, Wang, Zhou, Rui, Lou, Huifang, Duan, Shumin, Chen, Jiang Fan, Zhang, Baorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119815/
https://www.ncbi.nlm.nih.gov/pubmed/30210317
http://dx.doi.org/10.3389/fnbeh.2018.00185