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Implications of dimeric activation of PDE6 for rod phototransduction

We examine the implications of a recent report providing evidence that two transducins must bind to the rod phosphodiesterase to elicit significant hydrolytic activity. To predict the rod photoreceptor's electrical response, we use numerical simulation of the two-dimensional diffusional contact...

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Detalles Bibliográficos
Autores principales: Lamb, Trevor D., Heck, Martin, Kraft, Timothy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119862/
https://www.ncbi.nlm.nih.gov/pubmed/30068567
http://dx.doi.org/10.1098/rsob.180076