Low concentrations of clarithromycin upregulate cellular antioxidant enzymes and phosphorylation of extracellular signal-regulated kinase in human small airway epithelial cells

BACKGROUND: It is well known that low-dose, long-term macrolide therapy is effective against chronic inflammatory airway diseases. Oxidative stress is considered to be a key pathogenesis factor in those diseases. However, the mechanism of action of low-dose, long-term macrolide therapy remains uncle...

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Detalles Bibliográficos
Autores principales: Iwayama, Kuninori, Kimura, Junpei, Mishima, Aya, Kusakabe, Ayuko, Ohtaki, Ko-ichi, Tampo, Yoshiko, Hayase, Nobumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120091/
https://www.ncbi.nlm.nih.gov/pubmed/30186615
http://dx.doi.org/10.1186/s40780-018-0120-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120091/
https://www.ncbi.nlm.nih.gov/pubmed/30186615
http://dx.doi.org/10.1186/s40780-018-0120-4

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