Cargando…

Alpha-synuclein, Proteotoxicity and Parkinson's Disease: Search for Neuroprotective Therapy

BACKGROUND: There is a growing body of evidence in animal and cell based models of Parkinson's disease (PD) to suggest that overexpression and / or abnormal accumulation and aggregation of α-synuclein can trigger neuronal death. This important role of α-synuclein in PD pathogenesis is supported...

Descripción completa

Detalles Bibliográficos
Autores principales: Ganguly, Upasana, Chakrabarti, Sankha Shubhra, Kaur, Upinder, Mukherjee, Anwesha, Chakrabarti, Sasanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120113/
https://www.ncbi.nlm.nih.gov/pubmed/29189163
http://dx.doi.org/10.2174/1570159X15666171129100944