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Induction of ubiquitin C (UBC) gene transcription is mediated by HSF1: role of proteotoxic and oxidative stress

The polyubiquitin gene ubiquitin C (UBC) is considered a stress protective gene and is upregulated under various stressful conditions, which is probably a consequence of an increased demand for ubiquitin in order to remove toxic misfolded proteins. We previously identified heat shock elements (HSEs)...

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Detalles Bibliográficos
Autores principales: Bianchi, Marzia, Crinelli, Rita, Arbore, Vanessa, Magnani, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120222/
https://www.ncbi.nlm.nih.gov/pubmed/30186748
http://dx.doi.org/10.1002/2211-5463.12484