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Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer

We aimed to refine the value of CDX2 as an independent prognostic and predictive biomarker in colorectal cancer (CRC) according to disease stage and chemotherapy sensitivity in preclinical models. CDX2 expression was evaluated in 1045 stage I–IV primary CRCs by gene expression (n = 403) or immunohis...

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Detalles Bibliográficos
Autores principales: Bruun, Jarle, Sveen, Anita, Barros, Rita, Eide, Peter W., Eilertsen, Ina, Kolberg, Matthias, Pellinen, Teijo, David, Leonor, Svindland, Aud, Kallioniemi, Olli, Guren, Marianne G., Nesbakken, Arild, Almeida, Raquel, Lothe, Ragnhild A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120232/
https://www.ncbi.nlm.nih.gov/pubmed/29900672
http://dx.doi.org/10.1002/1878-0261.12347