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Crystal structure of the retroviral protease‐like domain of a protozoal DNA damage‐inducible 1 protein

DNA damage‐inducible 1 (Ddi1) is a multidomain protein with one of the domains being retropepsin‐like. HIV‐1 protease inhibitors were found to reduce opportunistic infections caused by pathogens like Leishmania and Plasmodium, and some of them were shown to inhibit the growth of these parasites. In...

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Detalles Bibliográficos
Autores principales: Kumar, Sushant, Suguna, Kaza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120238/
https://www.ncbi.nlm.nih.gov/pubmed/30186740
http://dx.doi.org/10.1002/2211-5463.12491