PGC1β regulates multiple myeloma tumor growth through LDHA‐mediated glycolytic metabolism

Multiple myeloma (MM) is an incurable hematologic malignancy due to inevitable relapse and chemoresistance development. Our preliminary data show that MM cells express high levels of PGC1β and LDHA. In this study, we investigated the mechanism behind PGC1β‐mediated LDHA expression and its contributi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Hongyu, Li, Ling, Chen, Qi, Li, Min, Feng, Jia, Sun, Ying, Zhao, Rong, Zhu, Yin, Lv, Yang, Zhu, Zhigang, Huang, Xiaodong, Xie, Weiguo, Xiang, Wei, Yao, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120252/
https://www.ncbi.nlm.nih.gov/pubmed/30051603
http://dx.doi.org/10.1002/1878-0261.12363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120252/
https://www.ncbi.nlm.nih.gov/pubmed/30051603
http://dx.doi.org/10.1002/1878-0261.12363

Ejemplares similares