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PGC1β regulates multiple myeloma tumor growth through LDHA‐mediated glycolytic metabolism
Multiple myeloma (MM) is an incurable hematologic malignancy due to inevitable relapse and chemoresistance development. Our preliminary data show that MM cells express high levels of PGC1β and LDHA. In this study, we investigated the mechanism behind PGC1β‐mediated LDHA expression and its contributi...
Autores principales: | Zhang, Hongyu, Li, Ling, Chen, Qi, Li, Min, Feng, Jia, Sun, Ying, Zhao, Rong, Zhu, Yin, Lv, Yang, Zhu, Zhigang, Huang, Xiaodong, Xie, Weiguo, Xiang, Wei, Yao, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120252/ https://www.ncbi.nlm.nih.gov/pubmed/30051603 http://dx.doi.org/10.1002/1878-0261.12363 |
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