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Imatinib Inhibits GH Secretion From Somatotropinomas

Background: Imatinib, a tyrosine kinase inhibitor, causes growth failure in children with chronic myeloid leukemia probably by targeting the growth hormone (GH)/insulin like growth factor-1 (IGF-1) axis. We aim to explore the imatinib targets expression in pituitary adenomas and study the effect of...

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Detalles Bibliográficos
Autores principales: Gupta, Prakamya, Rai, Ashutosh, Mukherjee, Kanchan Kumar, Sachdeva, Naresh, Radotra, Bishan Das, Punia, Raj Pal Singh, Vashista, Rakesh Kumar, Hota, Debasish, Srinivasan, Anand, Dhandapani, Sivashanmugam, Gupta, Sunil Kumar, Bhansali, Anil, Dutta, Pinaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120347/
https://www.ncbi.nlm.nih.gov/pubmed/30210447
http://dx.doi.org/10.3389/fendo.2018.00453