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Efficient design of cluster randomized trials with treatment‐dependent costs and treatment‐dependent unknown variances

Cluster randomized trials evaluate the effect of a treatment on persons nested within clusters, where treatment is randomly assigned to clusters. Current equations for the optimal sample size at the cluster and person level assume that the outcome variances and/or the study costs are known and homog...

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Detalles Bibliográficos
Autores principales: van Breukelen, Gerard J.P., Candel, Math J.J.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120518/
https://www.ncbi.nlm.nih.gov/pubmed/29888393
http://dx.doi.org/10.1002/sim.7824