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A five‐CpG DNA methylation score to predict metastatic‐lethal outcomes in men treated with radical prostatectomy for localized prostate cancer

BACKGROUND: Prognostic biomarkers for localized prostate cancer (PCa) could improve personalized medicine. Our group previously identified a panel of differentially methylated CpGs in primary tumor tissue that predict disease aggressiveness, and here we further validate these biomarkers. METHODS: Py...

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Detalles Bibliográficos
Autores principales: Zhao, Shanshan, Leonardson, Amy, Geybels, Milan S., McDaniel, Andrew S., Yu, Ming, Kolb, Suzanne, Zong, Hong, Carter, Kelly, Siddiqui, Javed, Cheng, Anqi, Wright, Jonathan L., Pritchard, Colin C., Lance, Raymond, Troyer, Dean, Fan, Jian‐Bing, Ostrander, Elaine A., Dai, James Y., Tomlins, Scott A., Feng, Ziding, Stanford, Janet L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120526/
https://www.ncbi.nlm.nih.gov/pubmed/29956356
http://dx.doi.org/10.1002/pros.23667