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Genetic variation of hepatitis B surface antigen among acute and chronic hepatitis B virus infections in The Netherlands

Genetic variation within hepatitis B surface antigen (HBsAg), in particular within the major hydrophobic region (MHR), is related to immune/vaccine and test failures and can have a significant impact on the vaccination and diagnosis of acute infection. This study shows, for the first time, variation...

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Detalles Bibliográficos
Autores principales: Cremer, Jeroen, Hofstraat, Sanne H. I., van Heiningen, Francoise, Veldhuijzen, Irene K., van Benthem, Birgit H. B., Benschop, Kimberley S. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120544/
https://www.ncbi.nlm.nih.gov/pubmed/29797607
http://dx.doi.org/10.1002/jmv.25232