Genetic instability and recurrent MYC amplification in ALK‐translocated NSCLC: a central role of TP53 mutations

The anaplastic lymphoma kinase (ALK) rearrangement defines a distinct molecular subtype of non‐small cell lung cancer (NSCLC). Despite the excellent initial efficacy of ALK inhibitors in patients with ALK+ lung cancer, resistance occurs almost inevitably. To date, there is no reliable biomarker allo...

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Detalles Bibliográficos
Autores principales: Alidousty, Christina, Baar, Till, Martelotto, Luciano G, Heydt, Carina, Wagener, Svenja, Fassunke, Jana, Duerbaum, Nicolai, Scheel, Andreas H, Frank, Sandra, Holz, Barbara, Binot, Elke, Kron, Anna, Merkelbach‐Bruse, Sabine, Ihle, Michaela A, Wolf, Jürgen, Buettner, Reinhard, Schultheis, Anne Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120547/
https://www.ncbi.nlm.nih.gov/pubmed/29885057
http://dx.doi.org/10.1002/path.5110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120547/
https://www.ncbi.nlm.nih.gov/pubmed/29885057
http://dx.doi.org/10.1002/path.5110

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