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A novel multifunctional anti-CEA-IL15 molecule displays potent antitumor activities
INTRODUCTION: Interleukin-15 (IL-15) is an immunomodulatory cytokine. It can activate and expand cytotoxic CD8 T lymphocytes and natural killer cells, leading to potent antitumor effects. Various forms of IL-15 are now in different stages of development for cancer immunotherapy. One of the major iss...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120566/ https://www.ncbi.nlm.nih.gov/pubmed/30214153 http://dx.doi.org/10.2147/DDDT.S166373 |