Inhibiting eEF-2 kinase-mediated autophagy enhanced the cytocidal effect of AKT inhibitor on human nasopharyngeal carcinoma

AIM: Our previous research showed that AKT inactivation via small molecule inhibitors did not induce significant apoptosis, but rather markedly increased autophagy in nasopharyngeal carcinoma (NPC). The purpose of the current study was to determine whether autophagy inhibition can enhance the antica...

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Detalles Bibliográficos
Autores principales: Zhao, Yuan-yuan, Tian, Ying, Liu, Lin, Zhan, Jian-hua, Hou, Xue, Chen, Xi, Zhou, Ting, Huang, Yan, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120571/
https://www.ncbi.nlm.nih.gov/pubmed/30214154
http://dx.doi.org/10.2147/DDDT.S169952

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120571/
https://www.ncbi.nlm.nih.gov/pubmed/30214154
http://dx.doi.org/10.2147/DDDT.S169952

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