Data driven diagnostic classification in Alzheimer's disease based on different reference regions for normalization of PiB-PET images and correlation with CSF concentrations of Aβ species

Positron emission tomography (PET) neuroimaging with the Pittsburgh Compound_B (PiB) is widely used to assess amyloid plaque burden. Standard quantification approaches normalize PiB-PET by mean cerebellar gray matter uptake. Previous studies suggested similar pons and white-matter uptake in Alzheime...

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Detalles Bibliográficos
Autores principales: Oliveira, Francisco, Leuzy, Antoine, Castelhano, João, Chiotis, Konstantinos, Hasselbalch, Steen Gregers, Rinne, Juha, Mendonça, Alexandre, Otto, Markus, Lleó, Alberto, Santana, Isabel, Johansson, Jarkko, Anderl-Straub, Sarah, Arnim, Christine, Beer, Ambros, Blesa, Rafael, Fortea, Juan, Sanna-Kaisa, Herukka, Portelius, Erik, Pannee, Josef, Zetterberg, Henrik, Blennow, Kaj, Moreira, Ana P., Abrunhosa, Antero, Nordberg, Agneta, Castelo-Branco, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120605/
https://www.ncbi.nlm.nih.gov/pubmed/30186764
http://dx.doi.org/10.1016/j.nicl.2018.08.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120605/
https://www.ncbi.nlm.nih.gov/pubmed/30186764
http://dx.doi.org/10.1016/j.nicl.2018.08.023

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