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Whole-genome bisulfite sequencing with improved accuracy and cost

DNA methylation patterns in the genome both reflect and help to mediate transcriptional regulatory processes. The digital nature of DNA methylation, present or absent on each allele, makes this assay capable of quantifying events in subpopulations of cells, whereas genome-wide chromatin studies lack...

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Detalles Bibliográficos
Autores principales: Suzuki, Masako, Liao, Will, Wos, Frank, Johnston, Andrew D., DeGrazia, Justin, Ishii, Jennifer, Bloom, Toby, Zody, Michael C., Germer, Soren, Greally, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120621/
https://www.ncbi.nlm.nih.gov/pubmed/30093547
http://dx.doi.org/10.1101/gr.232587.117