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Variant antigen repertoires in Trypanosoma congolense populations and experimental infections can be profiled from deep sequence data using universal protein motifs

African trypanosomes are vector-borne hemoparasites of humans and animals. In the mammal, parasites evade the immune response through antigenic variation. Periodic switching of the variant surface glycoprotein (VSG) coat covering their cell surface allows sequential expansion of serologically distin...

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Detalles Bibliográficos
Autores principales: Silva Pereira, Sara, Casas-Sánchez, Aitor, Haines, Lee R., Ogugo, Moses, Absolomon, Kihara, Sanders, Mandy, Kemp, Steve, Acosta-Serrano, Álvaro, Noyes, Harry, Berriman, Matthew, Jackson, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120623/
https://www.ncbi.nlm.nih.gov/pubmed/30006414
http://dx.doi.org/10.1101/gr.234146.118