Cargando…

Human proteins that interact with RNA/DNA hybrids

RNA/DNA hybrids form when RNA hybridizes with its template DNA generating a three-stranded structure known as the R-loop. Knowledge of how they form and resolve, as well as their functional roles, is limited. Here, by pull-down assays followed by mass spectrometry, we identified 803 proteins that bi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Isabel X., Grunseich, Christopher, Fox, Jennifer, Burdick, Joshua, Zhu, Zhengwei, Ravazian, Niema, Hafner, Markus, Cheung, Vivian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120628/
https://www.ncbi.nlm.nih.gov/pubmed/30108179
http://dx.doi.org/10.1101/gr.237362.118