KIF13A‐regulated RhoB plasma membrane localization governs membrane blebbing and blebby amoeboid cell migration

Membrane blebbing‐dependent (blebby) amoeboid migration can be employed by lymphoid and cancer cells to invade 3D‐environments. Here, we reveal a mechanism by which the small GTPase RhoB controls membrane blebbing and blebby amoeboid migration. Interestingly, while all three Rho isoforms (RhoA, RhoB...

Descripción completa

Detalles Bibliográficos
Autores principales: Gong, Xiaowei, Didan, Yuliia, Lock, John G, Strömblad, Staffan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120662/
https://www.ncbi.nlm.nih.gov/pubmed/30049714
http://dx.doi.org/10.15252/embj.201898994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120662/
https://www.ncbi.nlm.nih.gov/pubmed/30049714
http://dx.doi.org/10.15252/embj.201898994

Ejemplares similares