Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis

During apoptosis, pro‐apoptotic BAX and BAK are activated, causing mitochondrial outer membrane permeabilisation (MOMP), caspase activation and cell death. However, even in the absence of caspase activity, cells usually die following MOMP. Such caspase‐independent cell death is accompanied by inflam...

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Detalles Bibliográficos
Autores principales: Riley, Joel S, Quarato, Giovanni, Cloix, Catherine, Lopez, Jonathan, O'Prey, Jim, Pearson, Matthew, Chapman, James, Sesaki, Hiromi, Carlin, Leo M, Passos, João F, Wheeler, Ann P, Oberst, Andrew, Ryan, Kevin M, Tait, Stephen WG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120664/
https://www.ncbi.nlm.nih.gov/pubmed/30049712
http://dx.doi.org/10.15252/embj.201899238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120664/
https://www.ncbi.nlm.nih.gov/pubmed/30049712
http://dx.doi.org/10.15252/embj.201899238

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