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Master protocol trials in oncology: Review and new trial designs

In oncology, next generation sequencing and comprehensive genomic profiling have enabled the detailed classification of tumors using molecular biology. However, it is unrealistic to conduct phase I–III trials according to each sub-population based on patient molecular subtypes. Common protocols that...

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Detalles Bibliográficos
Autores principales: Hirakawa, Akihiro, Asano, Junichi, Sato, Hiroyuki, Teramukai, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120722/
https://www.ncbi.nlm.nih.gov/pubmed/30182068
http://dx.doi.org/10.1016/j.conctc.2018.08.009