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Rapid Screen of Potential i-Motif Forming Sequences in DNA Repair Gene Promoters

[Image: see text] We have studied the in vitro stability of 25 potential i-motif-forming DNA sequences found within the promoter regions of 18 different human DNA repair genes. Three widely available methods of characterization were used to rapidly assess i-motif folding and stability and comprise a...

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Detalles Bibliográficos
Autores principales: Rogers, R. Aaron, Fleming, Aaron M., Burrows, Cynthia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120732/
https://www.ncbi.nlm.nih.gov/pubmed/30198001
http://dx.doi.org/10.1021/acsomega.8b01551