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Suppression of IGF1R in Melanoma Cells by an Adenovirus-Mediated One-Step Knockdown System

Abnormal activation of the IGF1R signaling pathway accelerates melanoma development and metastases. RNAi systems with complex cloning procedures and unsatisfactory efficiency in suppressing gene expression have become the technical difficulties that hinder their utility when studying gene knockdown....

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Detalles Bibliográficos
Autores principales: Xin, Haoran, Lei, Mingxing, Zhang, Zhihui, Li, Jie, Zhang, Hao, Luo, Xinwei, Wang, Aoyun, Deng, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120749/
https://www.ncbi.nlm.nih.gov/pubmed/30161025
http://dx.doi.org/10.1016/j.omtn.2018.08.004