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Suppression of IGF1R in Melanoma Cells by an Adenovirus-Mediated One-Step Knockdown System
Abnormal activation of the IGF1R signaling pathway accelerates melanoma development and metastases. RNAi systems with complex cloning procedures and unsatisfactory efficiency in suppressing gene expression have become the technical difficulties that hinder their utility when studying gene knockdown....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120749/ https://www.ncbi.nlm.nih.gov/pubmed/30161025 http://dx.doi.org/10.1016/j.omtn.2018.08.004 |