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Structural basis for Scc3-dependent cohesin recruitment to chromatin

The cohesin ring complex is required for numerous chromosomal transactions including sister chromatid cohesion, DNA damage repair and transcriptional regulation. How cohesin engages its chromatin substrate has remained an unresolved question. We show here, by determining a crystal structure of the b...

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Detalles Bibliográficos
Autores principales: Li, Yan, Muir, Kyle W, Bowler, Matthew W, Metz, Jutta, Haering, Christian H, Panne, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120753/
https://www.ncbi.nlm.nih.gov/pubmed/30109982
http://dx.doi.org/10.7554/eLife.38356