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Class II histone deacetylases require P/Q-type Ca(2+) channels and CaMKII to maintain gamma oscillations in the pedunculopontine nucleus

Epigenetic mechanisms (i.e., histone post-translational modification and DNA methylation) play a role in regulation of gene expression. The pedunculopontine nucleus (PPN), part of the reticular activating system, manifests intrinsic gamma oscillations generated by voltage-dependent, high threshold N...

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Detalles Bibliográficos
Autores principales: Urbano, Francisco J., Bisagno, Verónica, Mahaffey, Susan, Lee, Sang-hun, Garcia-Rill, Edgar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120910/
https://www.ncbi.nlm.nih.gov/pubmed/30177751
http://dx.doi.org/10.1038/s41598-018-31584-2